Southbound lanes of the Pacific Highway were closed at Woolgoolga for a number of hours on Monday night.
Emergency services attended to a motor vehicle crash near Bark Hut Road at Woolgoolga.
The alarm was raised with Police and the Rural Fire Service just after 8:30pm.
According the Traffic Management Centre, southbound lanes were blocked while crews retrieve a vehicle that has left the road.
It was the second serious crash on the Highway within hours with crews attending a crash at Tyndale earlier in the afternoon.